Publications

41. Brugia malayi microfilariae adhere to human vascular endothelial cells in a C3-dependent manner
Jan-Hendrik Schroeder, David McCarthy, Tadge Szestak, Darren A. Cook, Mark J. Taylor, Alister G. Craig Charlotte Lawson, Rachel A. Lawren
PLOS Neglected tropical diseases
Published: May 8, 2017 https://doi.org/10.1371/journal.pntd.0005592

40. SiRNA and CRISPR/Cas9 Mediated Knockout of alpha ENAC
Tagalakis, A., van Haasteren, J., Aldossary, A., Rosa, L., Munye, M., McCarthy, D., & Hart, S. (2016). MOLECULAR THERAPY, 24, S11

39. Systematic Comparisons of Formulations of Linear Oligolysine Peptides with siRNA and Plasmid DNA
Kwok, A., McCarthy, D., Hart, S. L., & Tagalakis, A. D. (2016). CHEMICAL BIOLOGY & DRUG DESIGN, 87 (5), 747-763. doi:10.1111/cbdd.12709

38. A method for concentrating lipid peptide DNA and siRNA nanocomplexes that retains their structure and transfection efficiency
Tagalakis, A. D., Castellaro, S., Zhou, H., Bienemann, A., Munye, M. M., McCarthy, D, Hart, S. L. (2015). INTERNATIONAL JOURNAL OF NANOMEDICINE, 10, 2673-2683. doi:10.2147/IJN.S78935

37. Role of liposome and peptide in the synergistic enhancement of transfection with a lipopolyplex vector
Munye, M. M., Ravi, J., Tagalakis, A. D., McCarthy, D., Ryadnov, M. G., & Hart, S. L. (2015). SCIENTIFIC REPORTS, 5, ARTN 9292. doi:10.1038/srep09292

36. Anionic, Receptor-Targeted Nanocomplexes for Systemic and Neuronal Delivery of siRNA.
Tagalakis, A. D., Jayarajan, V., Bienemann, A. S., Lee, D. H., Zhou, H., McCarthy, D., & Hart, S. L. (2014). MOLECULAR THERAPY, 22, S135-S136. NATURE PUBLISHING GROUP.

35. PEGylation improves the receptor-mediated transfection efficiency of peptide-targeted, self-assembling, anionic nanocomplexes
Tagalakis, A. D., Kenny, G. D., Bienemann, A. S., McCarthy, D., Munye, M. M., Taylor, H., . . . Hart, S. L. (2014).. J Control Release, 174, 177-187. doi:10.1016/j.jconrel.2013.11.014

34. Anionic nanocomplexes for widespread brain dispersion by convection enhanced delivery and targeted gene expression
Tagalakis, A., Kenny, G., Bienemann, A., McCarthy, D., Munye, M., & Hart, S. (2013). HUMAN GENE THERAPY, 24 (5), A38.

33. Comparison of nanocomplexes with branched and linear peptides for siRNA delivery
Tagalakis, A. D., Saraiva, L., McCarthy, D., Gustafsson, K. T., & Hart, S. L. (2013). Biomacromolecules, 14 (3), 761-770. doi:10.1021/bm301842j

32. Development of Anionic Nanocomplexes for Targeted SiRNA and Plasmid DNA Delivery
Tagalakis, A. D., Kenny, G., Saraiva, L., McCarthy, D., & Hart, S. L. (2012). MOLECULAR THERAPY, 20, S248. NATURE PUBLISHING GROUP.

31. Fast gelation of self-assembling peptide nanofibres triggered by electromagnetic radiation heating
Mazza, M and Gaisford, S and McCarthy, D and Schatzlein, AG and Uchegbu, IF (2011) Fast gelation of self-assembling peptide nanofibres triggered by electromagnetic radiation heating. In: Technical Proceedings of the 2011 NSTI Nanotechnology Conference and Expo, NSTI-Nanotech 2011. (pp. 650- 653).

30. A study of size, microscopic morphology and dispersion mechanism of structures generated on hydration of proliposomes. Journal of Dispersion Science and Technology (2012) 33, 1121-1126.
Elhissi AMA, Ahmed W, McCarthy D, Taylor KMG Journal of Dispersion Science and Technology (2012) 33, 1121-1126.

29. A closer look at PLGA microspheres. InFocus. 17 (18-24).
D. McCarthy (2010).

28. Multiwalled carbon nanotube-doxrubicin supramolecular complexes for cancer therapeutics. Chemical Commun.,2008, 459-461
Hanene Ali-Boucetta, Khuloud T. Al-Jamal, David McCarthy, Maurizio Prato, Alberto Bianco and Kostas Kostarelos.

27.‘Poppy seeds’ in stomach aspirates: is oral omeprazole extemporaneous dispersion bioavailable? European Journal of Pediatrics. 2007 20th July.
Catherine Tuleu,1 Sara Arenas-Lopez3, Chris Robinson3, David McCarthy4, Richard I. J. Paget5, Shane Tibby5 and Kevin M. G. Taylor1

26. Carbohydrate based micelle clusters which enhance hydrophobic drug bioavailability by up to 1 order of magnitude, Biomacromolecules. 2006 Dec;7(12):3452 9.
Qu X, Khutoryanskiy VV, Stewart A, Rahman S, Sternberg Papahadjopoulos B, Dufes C, McCarthy D, Wilson CG, Lyons RL, Carter KC, Schätzlein AG, Uchegbu IF,.

25. Surface modification of adenovirus by zwitterionic (DMPC:Chol) liposomes can up-or down- regulate adenoviral gene transfer efficiency in vitro. Journal of Drug Delivery Science And Technology, 15 (4) 289-294 2005
R .Singh, D. McCarthy, K. Kostarelos.

24. Binding and Condensation of Plasmid DNA onto Functionalised Carbon Nanotubes: Towards the Construction of Nanotube-Based Gene Delivery Vectors. Journal of American Chemical Society.2005,127(12), 4388-96
R. Singh, D. Pantarotto, D. McCarthy, O. Caloin, J. Hoebeke, C. Partidos, J. Briand, M. Prato, A. Bianco, K. Kostarelos.

23. Functionalised carbon nanotubes for plasmid DNA gene delivery. Angewandte Chemie International Edition, 2004, 43,5242-5246.D.Pantarotto,
R.Singh, D.McCarthy, M.Erhardt, J-P.Briand, M.Prato*, K.Kostarelos*, A.Bianco*

22. Highly Hydrophilic Fused Aggregates (Microsponges) from a C12 Spermine Bolaamphiphile. J.Phys. Chem. B 2004. 108,8129-8135.
Kan,L. Papahadjopoulos-Sternberg B. Wong, D. Waigh, R. Watson, D. Gray, A. McCarthy, D. McAllister, M. Schatzlein, A. Uchegbu, I.

21. Liposome (Lipodine)-mediated DNA vaccination by the oral route. J. Liposome Res. 12, 185-197.
Perrie, Y., Obrenovic, M., McCarthy, D., & Gregoriadis, G. (2002).

20. Liposome-mediated DNA immunization via the oral route: In vitro stability and in vivo evaluation. 8th United Kingdom and Ireland Controlled Release Society Symposium 2002: Oral administration of `Difficult Drugs'.
Perrie, Y. Obrenovic, M, McCarthy, D. and Gregoriadis, G. (2002).

19. Liposomal DNA vaccines by the oral route. Proceedings of the Fifth International Conference, Liposome Advances: Progress in Drug and Vaccine Delivery, p. 35
Perrie, Y. Obrenovic, M, McCarthy, D. and Gregoriadis, G. (2001)

18. Oral Delivery of Liposome entrapped plasmid DNA generates Gene Expression and IgA Immune Responses against the encoded proteins. British Pharmaceutical Conference Science Proceedings. P 53.
Perrie, Y. Obrenovic, M, McCarthy, D. and Gregoriadis, G. (2001)

17. Morphological Studies of C16G2 Niasomes using Microscopy 3rd UKCRS Symposium on Controlled Drug Release. (January 1997)
P. Arunothayanun, M.S.Bernard, D. McCarthy, I. F.Uchegbu & A.T. Florence.

16. Phase transitions in aqueous dispersions of the hexadecyl diglycerol ether (C16 G2) non-ionic surfactant, cholesterol and cholesteryl poly-24-oxyethylene ether: vesicles, tubules, discomes and micelles. S.T.P Pharma Sciences 6 (1) 33-43 1996
I.F. Uchegbu, D. McCarthy, A. Schatzlein & A. T. Florence.

15. The extent of errors associated with contact angles 3. The influence of surface roughness effect on angles measured by a Wilhelmy plate technique for powders. Colloids and Surfaces A : Physicochemical And Engineering Aspects 95 (1995) 27-35
G. Buckton, P. Darcy & D. McCarthy.

14. Titanium dioxide (rutile) particle uptake from the rat G. I. tract and translocation to systemic organs after oral administration. International Journal of Pharmaceutics 105 (1994) 157-168
P. Jani, D. McCarthy & A. T. Florence

13. The uptake and translocation of micro particulate matter from the rat G. I. tract and translocation to systemic organs after oral administration. British Toxicology Society Abstract, March 1994 P50-51
P. Jani, D. McCarthy & A. T. Florence.

12. Apoptosis as a mechanism of Tributlytin Cytotoxicity to thymocytes: Relationship of Apopotic markers to Biochemical and Cellular effects. Toxicology & Applied Pharmacology 119 122-130 (1993)
M. Raffray, D. McCarthy, R. Snowden & G. Cohen.

11. Nanosphere and Microsphere uptake via Peyer’s patches, observations of the rate of uptake in the rat after a single oral dose. International Journal of Pharmaceutics 86, 1992 239-246
P. Jani, D. McCarthy & A. T. Florence.

10. Further histological evidence or the gastrointestinal absorption of polystyrene nanospheres in the rat. International Journal of Pharmaceutics 84, 1992, 245-252
P. Jani, D. McCarthy & A. T. Florence.

9. Quantification of the growth and remodelling changes induced by subchronic administration of the synthetic retinoids 13-cis-retinoic acid (CRA) and etretinate (ETR) in the rat. Human & Experimental Toxicology 1992.
A. T. Keene, D. McCarthy, M. Blades & J. Turton.

8. Activation of Programmed cell death in immature rat thymocytes by bis (tri-n-butyltin) oxide TbTo : 1 Morphological studies. Journal of Human & Experimental Toxicology 1992 Vol. 10 No.6 481-2
M. Raffray, D. McCarthy & G. Cohen.

7. P15 The synthetic retinoids 13-cis-retinoic acid (CRA) and etretinate (ETR) cause premature closure of the long bone epiphysis and the irreversible arrest of longitudinal bone growth in the Guinea Pig. Bone (1992) 13, 278.
A. T. Keene, H. Fernhead, D. McCarthy, M. Tucker & J. Turton.

6. Polystyrene Microspheres uptake and translocation via gastrointestinal tract mucosa after oral dose. Science Sessions, British Pharmaceutical conference, Liverpool (Sept. 1991) P. Jani, D. McCarthy & A. T. Florence.

5.Toothpaste and Crohns disease. Lancet letter 29th December 1990
A. T. Florence, P. Jani & D. McCarthy.

4. The Mechanism of action of Capsaicin on sensory C Type Neurons and their Axons in Vitro. Neuroscience Vol 23 No.1 pp 275-289 1987.
S. J. Marsh, C. E. Stansfield, D. A. Brown, R. Davey & D. McCarthy.

3. Reversibility of 13-cis-Retinoic Acid-induced long bone re-modelling in the rat. Human Toxicology 1986, 5, 410
J. Lovett, J. Turton, D. McCarthy, R. M. Hicks & E. Katchburian.

2. Interactions of Body Fluids with Liposomes in Vitro. Journal of Pharmacy & Pharmacology 35 (1983)
R. S. Chawla, R. Fleming & D. McCarthy.

1. Localisation of Enzymes and Alkaloidal Metabolites in Papaver Latex. Archives of Biochemistry and Biophysics. Vol 222, No.2 pp.599-606 April 15 1983.
M. F. Roberts, D. McCarthy, T. M. Kutchan & C. J. Coscia